Hormone Pharmacology Information
Pro Hormones
Nomenclature/Chemical naming info:
For reference:
etioallocholan = 5a-androst = ‘a skeleton’ or ‘a isomer’
etiocholan = 5b-androst = ‘b skeleton’ or ‘b isomer’
17beta-hydroxy = 17b-ol
estra = 19-norandrost
1-AD (1-androstenedione) 1-androstene-3b,17b-dione or androst-1-ene-3b,17b-dione
1-AD (1-androstenediol) 1-androstene-3b,17b-diol or androst-1-ene-3b,17b-diol
4-AD (4-androstenedione) 4-androstene-3b,17b-dione or androst-4-ene-3b,17b-dione
4-AD (4-androstenediol) 4-androstene-3b,17b-diol or androst-4-ene-3b,17b-diol
1,4AD (Boldione) 1,4-androstadiene-3b,17b-dione or androst-1,4-diene-3b,17b-dione
M1,4AD (Dianadiol) 17a-methyl-1,4-androstadiene-3b,17b-diol or 17a-methyl-androst-1,4-diene-3b,17b-diol
19-Tren X (Pro-Dienolone) 19-norandrosta-4,9-diene-3b,17b-dione or estra-4,9-diene-3b,17b-dione
Max LMG 13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one
Orastan-A (Furazabol THP) 5a-androstano[2,3-c]furazan-17b-tetrahydropyranol ether
Orastan-E (Stanozol THP) [3,2-c]pyrazole-5alpha-etioallocholane-17b-tetrahydropyranol
Halodrol-50 (Turinadiol) 4-chloro-17a-methyl-androst-1,4-diene-3b,17b-diol
Promagnon-25 (Methyl-Clostediol) 4-chloro-17a-methyl-androst-4-ene-3b,17b-diol
Propadrol 12-ethyl-3-methoxy-gona-diene-17 6-17 dihydroxyetiocholove-3-ol proponate
11-OXO (Adrenosterone) 4-androstene-3,11,17-trione or 11-oxo-androstenedione
Methoxy-TRN 17b-methoxy-trienbolone
Methoxy-TST 17b-methoxy-trienosterone
19-Nor (19-norandrostenediol) 19-nor-4-androsten-3b,17b-diol or 19-norandrost-4-ene-3b,17b-diol
5AA (5-alpha-androstanediol) 5a-androstane-3b,17b-diol
M5AA (Mestanolone) 17a-methyl-5a-androstanediol
3-Alpha (3-alpha-androstanediol) 5a-androstane-3alpha,17b-diol
M1T (Methyl 1-Test aka 17aa-1-testosterone) 17a-methyl-1-androstene-3-one-17b-ol or 17a-methyl-5a-androst-1-ene-3-one-17b-ol
Superdrol (Methyldrostanolone) 2a,17a-dimethyl-5a-androst-3-one-17b-ol or 2a,17a-dimethyl-etiocholan-3-one-17b-ol
Pheraplex (Madol or DMT) 17a-methyl-etioallocholan-2-ene-17b-ol or 17a-methyl-5a-androst-2-ene-17b-ol
Ergomax LMG (Ergo Matrix) 17a-methyl-delta-2-etioallocholane
Epithio (Havoc or Epistane) 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol or 2a,3a-epithio-17a-methyl-etioallocholan-17b-ol
Methyl-D (Methyl Dienolone) 17a-methyl-19-Norandrosta-4,9(10)-diene-3-one-17b-ol or 17a-methyl-17b-hydroxy-estra-4,9(10)-diene-3-one
M4OHN (Methylhydroxynandrolone) 17a-methyl-4-hydroxy-19-norandrost-4-ene-3-one or 17a-methyl-4-hydroxy-estra-4-ene-3-one
4OHT (hydroxytestosterone) 4-hydroxy-androst-4-ene-3-one-17b-ol or 4,17-dihydroxy-androst-4-ene-3-one
MDHT (methyl-DHT/mestanolone) 17a-methyl-5a-androstane-3-one
According to Wikipedia, "Steroidogenesis is the process wherein desired forms of steroids are generated by transformation of other steroids. The pathways of steroidogenesis can differ from organism to organism, but the pathways of human steroidogenesis are shown in the figure". Products of steroidogenesis include:
- Androgens
- Testosterone
- Estrogens and progesterone
- Corticoids
- Cortisol
- Aldosterone
I think this is a useful reference chart from Wikipeida to pathways of formation of testosterone from cholesterol, or if you are taking a pro hormone, for example the original 1-AD (1-androstenedione), you can locate it in the chart and see how close it is to testosterone and its pathway. You can also see how estrogens are also formed from testosterone precursors as well as testosterone. No wonder the original 1-AD was so beloved by bodybuilders when it was on the market; it is one step away from conversion to testosterone! Dually note that it converts to estrone then estrodiol as well….thats not so good. Some conversion is necessary but to much is bad and will result in side effects such as gynocomastia. Remember a previous article that I posted (from Muscular Development) on the necessity of the presence of cholesterol for testosterone increases and protein synthesis! Hence you need cholesterol to build muscle, and the no or low cholesterol diets are not in the best interest of anabolism.
Below is information such as estimated half life and A:A ratio’s on certain compounds. I’ll update more as I find further info as much of it is compiled from original manufacturer claims and as such this should be used for reference purposes only. If anyone sees anything they can add or change please let me know. Anabolic to Androgenic ratio’s based on original manufacture claims and Vida info. Note many other unseen factors come into play that aren’t apparent in the ratio’s such as progesterone activity, and how ‘strongly’ a compound binds to the androgen receptors. For example Masteron has a relatively low A:A ratio and a pretty low androgenic # of about 25 but it binds very strongly and/or with high affinity compared to other compounds. Q-Factor is the anabolic # divided by androgenic #. Some anabolics are listed with a ‘range’ for the most accurate possible estimate. Methyl Testosterone is the oral of which all other orals are compared, just as IM Test is to other injectibles: